Parkinson’s disease starts in the brain. Certain nerve cells break down or die. As a result, the levels of dopamine, a chemical in your brain, begin to fall. When your dopamine levels decrease, it causes your brain to act in unusual ways and leads to impaired movement, among other things.
Parkinson’s disease affects around 1% of people older than 60 and 5% of people over 85. It is a disease that typically appears after the age of 60.
There is still much we have yet to learn about Parkinson’s disease. Unfortunately, there is no cure yet. Many of the forms of treatment for the disease only manage the symptoms. The exact cause of Parkinson’s is still unclear.
Scientists believe that factors like genes and exposure to certain toxins may increase your likelihood for getting Parkinson’s. They have also linked the presence of a certain type of protein found in the brain to Parkinson’s disease.
We also know that younger people rarely experience Parkinson’s, having a relative that has Parkinson’s increases your chance of getting it, and that men are more likely to get it than women.
At first, the symptoms of Parkinson’s may be subtle. They usually begin on one side of your body and are more present on that side even when they progress to your whole body.
These symptoms could be:
The onset of symptoms differs with different people. It can look like normal signs of aging because the symptoms appear so gradually. You might feel some mild shaking in your hand or have mobility issues at first, or you might start speaking slower or more softly.
However, you will eventually start to walk and stand leaning forward and do specific things with your arms. You will also start to experience symptoms on one side of the body. Many people first feel stiff, have a tremor, experience sleep difficulties, have constipation, experience loss of smell, or have restless legs before any other symptom.
Since there is no known treatment for Parkinson's, treatment is all about symptom management. There are different medications, surgeries, and other methods to help with the symptoms.
Medicines used to treat Parkinson’s often:
The most common medication for Parkinson’s is called levodopa, or L-dopa. Levodopa helps the brain make more dopamine. Unfortunately, levodopa can cause nausea, vomiting, low blood pressure, and sleep difficulties. That is why people usually take a medication called carbidopa alongside levodopa. Carbidopa helps to reduce those side effects.
People who take these medications should always consult their doctor before they stop taking them. Suddenly stopping these medications can have serious and unwanted effects.
Other medications that people take for Parkinson’s include:
Some people may not respond well to these medications. In that case, a surgery called deep brain stimulation, or DBS, could be a good option. This is a procedure where the surgeon places electrodes in the brain that connect to another device in the chest. Together, the device and electrodes help to stop many Parkinson’s symptoms like tremors, slow movement, and muscle stiffening.
Other ways to treat Parkinson’s symptoms include physical, occupational, and speech therapies. These can help with the physical, vocal, and mental effects of Parkinson’s. You can also use exercise and diet to help with muscle and balance issues.
SOURCE: WEBMD